Avastin 25mg/ml (bevacizumab)
What is Avastin 25mg/ml (bevacizumab) ?
Avastin 25mg/ml (bevacizumab) can rarely cause a tear in the stomach/intestines (gastrointestinal perforation). It may also increase the risk of serious (possibly fatal) bleeding, such as bleeding from the stomach/intestines or in the brain.
Avastin 25mg/ml (bevacizumab) is typically given along with other chemotherapy treatments. It’s often used as a second-line treatment or given when cancers have spread to other areas of the body
Each vial contains bevacizumab 25 mg/mL as either bevacizumab 100 mg in 4 mL or bevacizumab 400 mg in 16 mL. Nonmedicinal ingredients: α,α-trehalose dihydrate, polysorbate 20, sodium phosphate and water for injection. Preservative-free.
How Avastin works ?
Avastin is a man-made antibody (IgG1) used to treat kidney, colon, and rectal cancer. Bevacizumab is also used to treat lung cancer (non-small cell type) and certain types of brain tumors. This drug works by blocking a certain protein (vascular endothelial growth factor-VEGF) thereby decreasing the blood supply to the tumor and slowing tumor growth.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used to treat a certain serious eye condition (age-related macular degeneration).
The following side effects become severe or don’t go away:
Loss of appetite
Change in taste
High blood pressure
Sores on the skin or in the mouth
Serious Side Effects of Avastin
Contact your doctor immediately if you experience any of the symptoms listed in the Warning section, or any of the following serious side effects:
Gagging, coughing, or choking after drinking or eating
Slow or difficult speech
Dizziness or fainting
Weakness or numbness of an arm or leg
Pain in the arms, neck, or upper back
Shortness of breath
Vision loss or changes in vision
Signs of infection, which may include fever, chills, or sore throat
Unexplained weight gain
Swelling of the eyes, face, stomach, hands, feet, ankles, or lower legs
Dry, hacking cough
Itching, redness, or scaling of the skin.
There may be an interaction between bevacizumab and any of the following:
bacillus Calmette-Guérin (BCG)
Doxorubicin (Adriamycin, Rubex)